Timeline: UCSC leadership in genomics
Building a national data hub for cancer genomics is among the recent milestones in a long history of UCSC leadership in the field of genomics. The following timeline lists some of UCSC's major contributions to the field.
- 1985: Chancellor Robert Sinsheimer convenes a group of eminent biologists in Santa Cruz to propose a massive project to determine the complete DNA sequence of the human genome--our genetic blueprint.
- 1990: International Human Genome Project launched with the goal of a complete human genome sequence by 2005.
- December 1999: UCSC's David Haussler joins the project to locate the genes in the human genome sequence and enlists molecular biology graduate student Jim Kent.
- June 22, 2000: UCSC assembles the human genome sequence using Kent's 10,000-line computer program.
- July 7, 2000: The UCSC genome bioinformatics group releases the first working draft of the human genome sequence on the web. Scientists download half a trillion bytes of information from the UCSC genome server in the first 24 hours.
- September 2000: Kent develops the UCSC Genome Browser, which becomes an essential resource to biomedical science.
- May 2004: Haussler's group publishes findings about ultra-conserved elements in the human genome that have remained unchanged through long periods of evolutionary history--one of Science magazine's breakthroughs of the year.
- March 2009: UCSC Cancer Genomics Browser makes its debut, built on the UCSC Genome Browser platform and capable of visualizing data from cancer clinical trials.
- November 2009: Haussler and an international team of collaborators launch the Genome 10K project to sequence the genomes of 10,000 vertebrate species.
- May 2010: The Neanderthal genome draft sequence is posted on the UCSC Genome Browser and published with scientific findings in Science by UCSC's Richard E. (Ed) Green.
- August 2011: Haussler's group begins work on national data center for cancer genomics.
- May 2012: The Cancer Genomics Hub (CGHub) provides cancer researchers nationwide with efficient access to a large and rapidly growing store of biomedical data.
- June 5, 2013: As a member of the organizing committee, David Haussler helps launch the Global Alliance for Genomics and Health, an international, non-profit alliance formed to help accelerate the potential of genomic medicine to advance human health.